22 days in Panama Itinerary

Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.

Step off the beaten path and head to Iglesia de la Merced and Iglesia de San José. Shop till you drop at Multicentro Mall and Weil Art Gallery. Step out of Panama City to go to Portobelo and see Scuba & Snorkeling, which is approximately 1h 50 min away. There's lots more to do: get to know the fascinating history of Casco Viejo, take an in-depth tour of Museo del Canal Interoceanico de Panama, make a trip to Avenida Balboa, and delve into the distant past at Panama La Vieja.

To see ratings, photos, more things to do, and tourist information, refer to the Panama City road trip tool.

Willemstad, Curacao to Panama City is an approximately 5.5-hour flight. Due to the time zone difference, you'll gain 1 hour traveling from Willemstad to Panama City. Expect a daytime high around 36°C in July, and nighttime lows around 29°C. You'll have a few hours on the 24th (Wed) to wrap things up before traveling to Bocas Town.

The colorful and relaxed Bocas Town has a welcoming atmosphere, with the modestly sized urban area showcasing typical Caribbean clapboard houses and home to a mixed community from across the world.

We've included these beaches for you: Wizard Beach and Starfish Beach. Your cultural itinerary includes sights like Plastic Bottle Village and Smithsonian Tropical Research Institute. Step out of Bocas Town to go to Bluff Beach and see Playa Bluff, which is approximately 30 minutes away. There's more to do: shop like a local with Up In The Hill and discover the deep blue sea with a scuba or snorkeling tour.

You can plan Bocas Town trip in no time by asking Inspirock to help create your itinerary.

Getting from Panama City to Bocas Town by flight takes about 2.5 hours. Other options: do a combination of taxi, bus, and ferry. Expect little chillier weather when traveling from Panama City in July: highs in Bocas Town hover around 30°C, while lows dip to 30°C. On the 28th (Sun), you're off to Boquete.

Now known internationally for its fresh mountain air, year-round pleasant temperatures, and large community of North American expats, Boquete has changed rapidly since the start of the century, changing from a humble mountain town, into a humble mountain surrounded by gated communities and estates.

Eschew the tourist crowds and head to Volcan Baru National Park and Los Ladrillos. Get outdoors at River Rafting & Tubing and Los Cangilones de Gualaca. There's more to do: enjoy some diversion at Boquete Buggies and look for gifts at The Zapadora.

To find where to stay, ratings, traveler tips, and tourist information, read our Boquete online trip itinerary planner.

Getting from Bocas Town to Boquete by combination of ferry and taxi takes about 4 hours. Other options: do a combination of ferry and bus. Finish your sightseeing early on the 1st (Thu) so you can drive to Santa Catalina.

Since Santa Catalina became known in the international surfing community in the 1970s, it has done well to maintain its identity as a tucked-away fishing village.

Kick off your visit on the 1st (Thu): meet some fierce fish with a shark diving experience. Get ready for a full day of sightseeing on the next day: see Rancho Estero and then tour the pleasant surroundings at Lagartero Beach.

To find reviews, photos, other places to visit, and tourist information, use the Santa Catalina online tour itinerary builder.

You can drive from Boquete to Santa Catalina in 5.5 hours. Alternatively, you can do a combination of bus and taxi. Wrap up your sightseeing on the 3rd (Sat) early enough to drive to El Valle de Anton.

Surrounded by lush forests and spectacular mountains, El Valle de Anton serves as the perfect spot to enjoy some of Panama's finest natural attractions.

Step off the beaten path and head to Butterfly Haven and Farallon Butterflies. Visiting El Palmar Beach and Vista Mar Golf Beach & Marina will get you outdoors. Step out of El Valle de Anton to go to Rio Hato and see Leading Adventures, which is approximately 1h 5 min away. Spend the 5th (Mon) exploring nature at Gaital National Park. It doesn't end there: stroll through Aprovaca (The Orchid Nursery & Conservation Center) and get engrossed in the history at The Anton Valley Historical and Cultural Museum.

To see more things to do, photos, traveler tips, and more tourist information, you can read our El Valle de Anton trip itinerary planning tool.

Getting from Santa Catalina to El Valle de Anton by car takes about 5 hours. Other options: do a combination of taxi, flight, and bus; or take a bus. Wrap up your sightseeing by early afternoon on the 6th (Tue) to allow enough time to drive to Panama City.

Step off the beaten path and head to Bahai Temple and Panama Rainforest Discovery Center. Satisfy your inner culture vulture at El Arco Chato and Karavan Gallery. Enjoy Panama City some more: test your team's savvy at popular escape rooms, wander the streets of Cinta Costera, cast your line with a fishing tour, and take in the exciting artwork at Nina Concept Store.

To see ratings, reviews, other places to visit, and more tourist information, you can read our Panama City sightseeing planning site.

Traveling by car from El Valle de Anton to Panama City takes 2.5 hours. Alternatively, you can do a combination of bus and taxi; or do a combination of bus and subway. You'll have a few hours on the 10th (Sat) to wrap things up before traveling home.